Glycosyl phenylthiosulfonates (glyco-PTS): novel reagents for glycoprotein synthesis.
نویسندگان
چکیده
Controlled site-selective glycosylation can be achieved by combining site-directed cysteine mutagenesis with chemical modification of the introduced thiol; a new class of more efficient chemoselective reagents, glycosyl phenylthiosulfonates, allow rapid glycosylations of representative simple thiols, peptides and proteins.
منابع مشابه
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 1 21 شماره
صفحات -
تاریخ انتشار 2003